Cooperstown got three touchdowns from Lucas Lyons and two more from Michael Perrino to cap a big comeback.
The Hawkeyes beat New York Mills 38-36, getting the winning score with :34 left in the game. Perrino tied the game with his second rushing touchdown. Lyons then ran in the two-point conversion.
Lyons finished with a season-best 252 rushing yards on 34 carries for Cooperstown, which got 94 ground yards on 17 carries from Perrino.
First-year head coach Joe Pestar earned his first victory as head coach of Cooperstown (1-6), which plays in the Class D East Division.
Cooperstown had lost 13 straight games over two seasons since last beating Mills in the 2012 season-opener, 43-20.
The Hawkeyes (1-6) play at Mount Markham on Oct. 25 at 7 p.m. in their cross-over game. The Mustangs (0-7) were last in C East.
Cooperstown 38, NYM 36
New York Mills 22 0 6 8 - 36
Cooperstown 0 8 14 16 - 38
C - Lucas Lyons 4 run (Joe Harmon pass from Carmen Booan)
C - Lucas Lyons 3 run (kick failed)
C - Lucas Lyons 4 run (Lucas Lyons run)
C - Mike Perrino 4 run (Max Bonderoff pass from Carmen Booan)
C - Mike Perrino 2 run (Lucas Lyons run)
Cooperstown rushing: Lucas Lyons 34-252, Joe Harmon 6-29, Mike Perrino 17-94, Nick Fanion 2-9, Carmen Booan 1-3.
Cooperstown passing: Carmen Booan 3-for-6, 18 yards.
Cooperstown receiving: Joe Harmon 1-2, Max Bonderhoff 2-16.